THE ENDOCRINE OUTCOME AFTER SURGICAL REMOVAL OF CRANIOPHARYNGIOMAS

被引：62

作者：

CURTIS, J

DANEMAN, D

HOFFMAN, HJ

EHRLICH, RM

机构：

[1] HOSP SICK CHILDREN,DIV ENDOCRINOL,TORONTO M5G 1X8,ON,CANADA

[2] HOSP SICK CHILDREN,DIV NEUROSURG,TORONTO M5G 1X8,ON,CANADA

[3] UNIV TORONTO,TORONTO,ON,CANADA

来源：

PEDIATRIC NEUROSURGERY | 1994年 / 21卷

关键词：

GROWTH; WEIGHT GAIN; RECURRENCE; ENDOCRINE PROBLEMS; CRANIOPHARYNGIOMA;

D O I：

10.1159/000120858

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The postoperative course of children undergoing surgery for craniopharyngioma was reviewed. Typically they were below height at presentation. Ah had an attempt at radical surgical resection of the tumor. Most developed diabetes insipidus in the postoperative period, which was permanent in all but 1 child. 94% required thyroid replacement therapy, and sex steroids were administered in 100% when they reached the age of puberty. 91% required maintenance corticosteroids. 54% required growth hormone replacement, but some children showed continued growth despite apparent growth hormone deficiency. Postoperative obesity develops in one half of patients, and may be improved with administration of growth hormone; a controlled trial is underway.

引用

页码：24 / 27

页数：4

共 10 条

[1]

BLETHEN S L, 1987, Pediatrician, V14, P242

[2] INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II, PROLACTIN, AND INSULIN IN 19 GROWTH-HORMONE DEFICIENT CHILDREN WITH EXCESSIVE, NORMAL, OR DECREASED LONGITUDINAL GROWTH AFTER OPERATION FOR CRANIOPHARYNGIOMA [J].