SPONTANEOUS-ABORTION IN A HOSPITAL POPULATION - ARE TOBACCO AND COFFEE INTAKE RISK-FACTORS

被引：48

作者：

DOMINGUEZROJAS, V

DEJUANESPARDO, JR

ASTASIOARBIZA, P

ORTEGAMOLINA, P

GORDILLOFLORENCIO, E

机构：

[1] Cátedra de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad Complutense de Madrid and Hospital '12 de Octubre', Madrid

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1994年 / 10卷 / 06期

关键词：

ALCOHOL CONSUMPTION; COFFEE CONSUMPTION; HOSPITAL WORKERS; LOGISTIC REGRESSION; MISCARRIAGE; SPONTANEOUS ABORTION; TOBACCO SMOKING;

D O I：

10.1007/BF01719278

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The objective of this study was to examine the possible relationships between spontaneous abortion and caffeine, tobacco and alcohol intake in a well-controlled group of hospital workers. A retrospective cohort study design including 711 women, 20 to 41 years old, was used. All data regarding the purpose of this study were extracted from clinical histories registered at the Preventive Medicine Service. The dependent variable was spontaneous abortion and the independent variables were tobacco, coffee, and alcohol intake. Age, previous spontaneous abortion, menarcheal age and marital status were considered as potential confounders. The data were analyzed by multiple logistic regression. The following adjusted odds ratios of spontaneous abortion by caffeine consumption were calculated: 141-280 mg/day, 2.20 (1.22-3.96); 281-420 mg/day, 4.81 (2.28-10.14) and 421 or more, 15.43 (7.38-32.43); p < 0.05. The adjusted odds ratio for tobacco were 11 or more cigarettes/day, 3.35 (1.65-6.92); P < 0.05. It appears from this and other papers that tobacco and caffeine intake must be considered as clear risk factors for spontaneous abortion or miscarriage.

引用

页码：665 / 668

页数：4

共 35 条

[1]

Aborto espontáneo y provocado Servicio de informes t écnicos, 461, pp. 5-55, (1970)

[2]

Wilcox A.J., Weinberg C.R., Baird D.D., Risk factors for early pregnancy loss, Epidemiology, 1, pp. 382-385, (1990)

[3]

Edmons D.K., Lindsay K.S., Miller J., Early embryonic mortality in women, Fertil Steril, 38, pp. 447-451, (1982)

[4]

Miller J.F., Williamson E., Lancet, pp. 554-557, (1980)

[5]

Dominguez-Rojas V., Calle M.E., Ortega P., Astasio P., Valero J., del Rey Calero J., Abordaje epidemiológico del aborto espontáneo. Estudio de factores obstétricos y ginecológicos, Toko-Gin Práct, 49, 5, pp. 265-270, (1990)

[6]

Dominguez-Rojas V., Calle M.E., Ortega P., Astasio P., Valero J., del Rey Calero J., Adjusting risk factors in spontaneous abortion by multiple logistic regression, Eur J Epidemiol, 7, pp. 171-174, (1991)

[7]

Gustavii B., Miscarriage rate in women aged 35 years or more, Contr Gynec Obstet, 15, pp. 45-49, (1986)

[8]

Triolo O., Stella N.C., Dugo C., Corrado F., Abortivita spontanea ed eta materna avanzata, Minerva Ginecol, 42, 9, pp. 345-346, (1990)

[9]

Reginald P.W., Beard R.W., Chappie J., Forbes P.B., Liddell H.S., Mowbray J.F., Underwood J.L., Outcome of pregnancies progressing beyond 28 weeks gestation in women with a history of recurrent miscarriage, Br J Obstet Gynaecol, 94, pp. 643-648, (1987)

[10]

Stirrat G.M., Recurrent miscarriage II: Clinical associations, causes and management, Lancet, 336, pp. 728-733, (1990)

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