PHARMACOLOGICALLY ACTIVE ACETYLENE COMPOUNDS .2. PROPYNL-SUBSTITUTED INDOLE DERIVATIVES

被引：27

作者：

NEUMEYER, JL

MOYER, UV

LEONARD, JE

机构：

[1] Arthur D. Little, Inc., Cambridge, Acorn Park

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 03期

关键词：

D O I：

10.1021/jm00303a026

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A number of novel acetylenic amines and amides attached to an indole and isoindoline nucleus have been synthesized. The compounds generally exhibited CNS depressant or stimulating effects at high dosage levels. Some of the compounds were found to be in vitro inhibitors of monoamine oxidase. © 1969, American Chemical Society. All rights reserved.

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页码：450 / &

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