A UV-SENSITIVE MUTANT OF ARABIDOPSIS DEFECTIVE IN THE REPAIR OF PYRIMIDINE-PYRIMIDINONE(6-4) DIMERS

被引：142

作者：

BRITT, AB ^{[1
]}

CHEN, JJ ^{[1
]}

WYKOFF, D ^{[1
]}

MITCHELL, D ^{[1
]}

机构：

[1] UNIV TEXAS,MD ANDERSON CANC RES CTR,DEPT CARCINOGENESIS,SMITHVILLE,TX 78957

来源：

SCIENCE | 1993年 / 261卷 / 5128期

关键词：

D O I：

10.1126/science.8372351

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Plants are continually subjected to ultraviolet-B (UV-B) irradiation (290 to 320 nanometers) as a component of sunlight, which induces a variety of types of damage to the plant DNA. Repair of the two major DNA photoproducts was analyzed in wild-type Arabidopsis thaliana and in a mutant derivative whose growth was sensitive to UV-B radiation. In wild-type seedlings, repair of cyclobutane pyrimidine dimers occurred more slowly in the dark than in the light; repair of this photoproduct was not affected in the mutant. Repair, in the dark, of pyrimidine-pyrimidinone(6-4) dimers was defective in the UV-sensitive mutant.

引用

页码：1571 / 1574

页数：4

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