ISOLATION AND PURIFICATION OF A REGULATING COFACTOR OF THE PENTOSE-PHOSPHATE PATHWAY

被引：34

作者：

RODRIGUEZSEGADE, S ^{[1
]}

CARRION, A ^{[1
]}

FREIRE, M ^{[1
]}

机构：

[1] UNIV SANTIAGO DE COMPOSTELA,FAC BIOL,DEPT BIOQUIM,SANTIAGO DE COMPOSTELLA,SPAIN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 89卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)90956-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cofactors that counteract the inhibition of glucose 6-phosphate dehydrogenase by NADPH, in the presence of GSSG, have been isolated and purified from mussel hepatopancreas and rat liver by gel filtration on Sephadex G-50 and polyacrylamide gel electrophoresis. The cofactors from mussel hepatopancreas and rat liver differ in apparent molecular wight, having values of 15,000 and 10,000 daltons, respectively. Both cofactors undergo inactivation by trypsin, while RNase and DNase have no effect on their activity. © 1979.

引用

页码：148 / 154

页数：7

共 10 条

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