A NEW ANTHELMINTIC CYCLODEPSIPEPTIDE, PF1022A

被引：116

作者：

SASAKI, T

TAKAGI, M

YAGUCHI, T

MIYADOH, S

OKADA, T

KOYAMA, M

机构：

[1] Pharmaceutical Research Laboratories, Meiji Seika Kaisha Ltd., Yokohama 222, Morooka-cho, Kohoku-ku

来源：

JOURNAL OF ANTIBIOTICS | 1992年 / 45卷 / 05期

关键词：

D O I：

10.7164/antibiotics.45.692

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The novel anthelmintic cyclodepsipeptide PF1022A was isolated from cultured mycelia of Mycelia Sterilia PF1022 (FERM BP-2671). It showed strong anthelmintic activities against Ascaridia galli in chickens. The structure of PF1022A was determined to be cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-methylleucyl-D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-methylleucyl) by spectroscopic analyses and chemical studies.

引用

页码：692 / 697

页数：6

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