LACK OF ANALGESIC ACTIVITY OF SUBSTANCE-P FOLLOWING INTRA-PERITONEAL ADMINISTRATION

被引：10

作者：

GOLDSTEIN, JM

MALICK, JB

机构：

[1] Biomedical Research Department ICI Americas Inc., Wilmington

来源：

LIFE SCIENCES | 1979年 / 25卷 / 05期

关键词：

D O I：

10.1016/0024-3205(79)90575-7

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Intraperitoneal administration of Substance P to rats did not result in significant analgesic activity. In addition, intraperitoneal administration of Substance P to mice also failed to result in significant analgesic activity. These results suggest a re-examination of the reported analgesic activity of peripherally administered Substance P. © 1979.

引用

页码：431 / 435

页数：5

共 7 条

[1] DUAL ACTIONS OF SUBSTANCE-P ON NOCICEPTION - POSSIBLE ROLE OF ENDOGENOUS OPIOIDS [J].