QUANTITATIVE STUDY OF THE STRUCTURE STABILITY RELATIONSHIP OF TCVO(III) COMPLEXES

被引：8

作者：

KUNG, HF ^{[1
]}

LIU, BL ^{[1
]}

WEI, Y ^{[1
]}

PAN, S ^{[1
]}

机构：

[1] BEIJING NORMAL UNIV,DEPT CHEM,BEIJING,PEOPLES R CHINA

来源：

APPLIED RADIATION AND ISOTOPES | 1990年 / 41卷 / 08期

关键词：

D O I：

10.1016/0883-2889(90)90026-D

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This paper describes the quantitative structure-stability relationship of TcvON2S2 compounds using a stability indicator based on the solid angle factor sum (SAS)_for predicting the in vitro stability. The SAS values of six TcvON2S2 and one TcvON4 (d,l-HMPAO) complexes were calculated from their x-ray crystallography data. The rank order of in vitro stability of these compounds, as measured by ligand exchange reaction, is directly related to that of the SAS values. The SAS values are potentially useful for predicting stability and designing new 99mTc radiopharmaceuticals. © 1990.

引用

页码：773 / 781

页数：9

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