POEMS SYNDROME WITH COMPLETE RECOVERY AFTER TREATMENT OF A SOLITARY PLASMACYTOMA

被引：22

作者：

BROUSSOLLE, E

VIGHETTO, A

BANCEL, B

CONFAVREUX, C

PIALAT, J

AIMARD, G

机构：

[1] HOP NEUROL, NEUROL CLIN, F-69394 Lyon 3, FRANCE

[2] FAC MED LYON, ANAT & CYTOL PATHOL LAB, Lyon, FRANCE

来源：

CLINICAL NEUROLOGY AND NEUROSURGERY | 1991年 / 93卷 / 02期

关键词：

POLYNEUROPATHY; POEMS SYNDROME; SOLITARY PLASMACYTOMA; NERVE BIOPSY; SURGERY; RADIATION THERAPY;

D O I：

10.1016/0303-8467(91)90061-S

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The P.O.E.M.S. syndrome is a rare clinical entity that has been described mainly in Japan. It is characterized by a progressive polyneuropathy with raised CSF protein content, organomegaly, endocrinopathy, skin changes and plasma cell dyscrasia. We report a new documented case associated with a solitary plasmocytoma of the 12th thoracic vertebra. Immunopathological and ultrastructural studies of the peripheral nerve did not disclose any immune-specific changes. Surgery and radiation therapy of the plasmocytoma allowed a complete recovery, with a 5-year follow-up. This case report illustrates the need for serial full skeletal survey, including scintigraphy, in middle-aged patients with progressive polyneuropathy of obscure origin.

引用

页码：165 / 170

页数：6

共 31 条

[1]

AIMARD G, 1984, REV NEUROL, V140, P510

[2] PLASMA-CELL DYSCRASIA WITH POLYNEUROPATHY, ORGANOMEGALY, ENDOCRINOPATHY, M PROTEIN, AND SKIN CHANGES - THE POEMS SYNDROME - REPORT ON 2 CASES AND A REVIEW OF THE LITERATURE [J].