INTRACEREBRAL PENETRATION OF INFRARED LIGHT

被引:180
作者
MCCORMICK, PW [1 ]
STEWART, M [1 ]
LEWIS, G [1 ]
DUJOVNY, M [1 ]
AUSMAN, JI [1 ]
机构
[1] HENRY FORD HOSP, HENRY FORD NEUROSURG INST, DETROIT, MI 48202 USA
关键词
INFRARED SPECTROSCOPY; OXIMETRY; TISSUE SPECTROSCOPY; INDOCYANINE GREEN; INTRAVASCULAR TRACERS;
D O I
10.3171/jns.1992.76.2.0315
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Near infrared transmission spectroscopy of the human cerebrum may allow noninvasive evaluation of cerebral hemoglobin saturation in humans. The emerging spectroscopy configuration for this application is a side-by-side source-receiver construct. The ability of this spectroscopy paradigm to detect changes in intracerebral attenuation by selective injection of the infrared tracer indocyanine green into the internal and external carotid arteries during endarterectomy is evaluated in five adult patients. In all five, simultaneous two-channel infrared transmission spectroscopy over the ipsilateral hemisphere documented tracer bolus transit with a signal-to-noise ratio greater than 100:1. In addition, the two channels could be configured to achieve depth resolution of the collected spectra.
引用
收藏
页码:315 / 318
页数:4
相关论文
共 32 条
[1]   MODEL FOR PHOTON MIGRATION IN TURBID BIOLOGICAL MEDIA [J].
BONNER, RF ;
NOSSAL, R ;
HAVLIN, S ;
WEISS, GH .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 1987, 4 (03) :423-432
[2]   EFFECTS OF CRYING ON CEREBRAL BLOOD-VOLUME AND CYTOCHROME AA3 [J].
BRAZY, JE .
JOURNAL OF PEDIATRICS, 1988, 112 (03) :457-461
[3]  
BRAZY JE, 1985, PEDIATRICS, V75, P217
[4]   COMPARISON OF TIME-RESOLVED AND TIME-UNRESOLVED MEASUREMENTS OF DEOXYHEMOGLOBIN IN BRAIN [J].
CHANCE, B ;
LEIGH, JS ;
MIYAKE, H ;
SMITH, DS ;
NIOKA, S ;
GREENFELD, R ;
FINANDER, M ;
KAUFMANN, K ;
LEVY, W ;
YOUNG, M ;
COHEN, P ;
YOSHIOKA, H ;
BORETSKY, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (14) :4971-4975
[5]   LIGHT EMITTING DIODE SKIN REFLECTANCE OXIMETER [J].
COHEN, A ;
WADSWORTH, N .
MEDICAL & BIOLOGICAL ENGINEERING, 1972, 10 (03) :385-+
[6]  
Cope M, 1988, Adv Exp Med Biol, V222, P183
[7]  
DELPY DT, 1987, SCAND J CLIN LAB INV, V47, P9
[8]   ESTIMATION OF OPTICAL PATHLENGTH THROUGH TISSUE FROM DIRECT TIME OF FLIGHT MEASUREMENT [J].
DELPY, DT ;
COPE, M ;
VANDERZEE, P ;
ARRIDGE, S ;
WRAY, S ;
WYATT, J .
PHYSICS IN MEDICINE AND BIOLOGY, 1988, 33 (12) :1433-1442
[9]  
Ferrari M, 1986, Adv Exp Med Biol, V200, P203
[10]  
GIANNINI I, 1982, PHYSIOL CHEM PHYS M, V14, P295