ENDOCYTOSIS OF CALCIUM-OXALATE CRYSTALS AND PROLIFERATION OF RENAL TUBULAR EPITHELIAL-CELLS IN A PATIENT WITH TYPE-1 PRIMARY HYPEROXALURIA

被引：87

作者：

LIESKE, JC

SPARGO, BH

TOBACK, FG

机构：

[1] UNIV CHICAGO,DEPT MED,5841 S MARYLAND AVE,MC 5100,CHICAGO,IL 60637

[2] UNIV CHICAGO,DEPT PATHOL,CHICAGO,IL 60637

来源：

JOURNAL OF UROLOGY | 1992年 / 148卷 / 05期

关键词：

CALCIUM OXALATE; URINARY CALCULI; HYPEROXALURIA; LIVER TRANSPLANTATION; KIDNEY TRANSPLANTATION;

D O I：

10.1016/S0022-5347(17)36954-9

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A patient with primary hyperoxaluria who received a liver-kidney transplant is presented. A postoperative renal biopsy showed apparent tubular cell endocytosis of calcium oxalate crystals and cell proliferation, indicating that renal epithelial cells do not perceive urinary crystals as inert. Such cellular responses to crystals may have a role in nephrolithiasis.

引用

页码：1517 / 1519

页数：3

共 16 条

[1]

COE FL, 1988, NEPHROLITHIASIS PATH

[2] MOLECULAR AND CLINICAL HETEROGENEITY IN PRIMARY HYPEROXALURIA TYPE-1 [J].