SEPARATIONS OF BASIC-AMINO-ACID BENZYL-ESTERS BY PH-ZONE-REFINING COUNTERCURRENT CHROMATOGRAPHY

被引：16

作者：

MA, Y ^{[1
]}

ITO, Y ^{[1
]}

机构：

[1] NHLBI,BIOPHYS CHEM LAB,BETHESDA,MD 20892

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 678卷 / 02期

关键词：

D O I：

10.1016/0021-9673(94)80470-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

pH-Zone-refining counter-current chromatography was applied to the separation of basic amino acid benzyl esters. The method uses a retainer base in the stationary phase to retain analytes in the column and an eluent acid to elute the analytes in the decreasing order of pK(a) and hydrophilicity. The preparative capability of the method is demonstrated in the separation of a 10-g quantity of the sample.

引用

页码：233 / 240

页数：8

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