POLYPHENOLS FROM ERIOSEMA-TUBEROSUM

被引:41
作者
MA, WG
FUZZATI, N
LI, QS
YANG, CR
STOECKLIEVANS, H
HOSTETTMANN, K
机构
[1] UNIV LAUSANNE,INST PHARMACOGNOISE & PHYTOCHIM,BEP,CH-1015 LAUSANNE,SWITZERLAND
[2] YUNNAN COLL TRADIT CHINESE MED,KUNMING 650011,PEOPLES R CHINA
[3] ACAD SINICA,KUNMING INST BOT,PHYTOCHEM LAB,650204 KUNMING,PEOPLES R CHINA
[4] UNIV NEUCHATEL,INST CHIM,CH-2000 NEUCHATEL,SWITZERLAND
关键词
ERIOSEMA TUBEROSUM; LEGUMINOSAE; ROOTS; POLYPHENOLS; ANTIFUNGAL COMPOUNDS;
D O I
10.1016/0031-9422(95)00052-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A dichloromethane extract of the roots of Eriosema tuberosum exhibited antifungal activity against Cladosporium cucumerinum and Candida albicans using TLC bioautography. Bioassay-directed fractionation led to the isolation of four new compounds, eriosemaones A-D, together with a known compound, flemichin-D, as the active constituents. Three inactive polyphenols were also isolated after methylation, together with one new chromone, eriosematin. Structures were determined by spectroscopic analysis and from chemical evidence.
引用
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页码:1049 / 1061
页数:13
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