JUMPING TRANSLOCATIONS INVOLVING BAND 3Q13.3 IN A CASE OF ACUTE MONOCYTIC LEUKEMIA

被引：36

作者：

REIS, MD

DUBE, ID

PINKERTON, PH

CHENLAI, J

ROBINSON, JB

KLOCK, RJ

SENN, JS

机构：

[1] SUNNYBROOK HLTH SCI CTR,DIV CLIN HEMATOL,TORONTO,ONTARIO,CANADA

[2] UNIV TORONTO HOSP,CANC CYTOGENET PROGRAM,TORONTO,ONTARIO,CANADA

来源：

CANCER GENETICS AND CYTOGENETICS | 1991年 / 51卷 / 02期

关键词：

D O I：

10.1016/0165-4608(91)90131-D

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a case of acute monocytic leukemia (FAB-5a) with a very aggressive clinical course and multiple chromosomal abnormalities. There were several sublines, each with trisomy 8 and a translocation involving 3q13.3 as a common breakpoint region. This region is an uncommon site of chromosomal breakage in malignancies and has not hitherto been reported as a breakpoint site in "jumping" translocations.

引用

页码：189 / 194

页数：6

共 16 条

[1] JUMPING TRANSLOCATION OF CHROMOSOME-14 IN A SKIN SQUAMOUS-CELL CARCINOMA FROM A XERODERMA PIGMENTOSUM PATIENT [J].