CSF-SUPPRESSED T2-WEIGHTED 3-DIMENSIONAL MP-RAGE MR-IMAGING

被引:11
作者
EPSTEIN, FH
MUGLER, JP
CAIL, WS
BROOKEMAN, JR
机构
[1] Depar1Ments of Radlology, Unlverslty of Vlrglnla Health Sciences Center, Charlottesvllle, Virginia
[2] Unlverslty of Vlrglnla Health Sciences Center, Charlottesvllle, Virginia
来源
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1995年 / 5卷 / 04期
关键词
BRAIN; MR STUDIES; FLUID-ATTENUATED INVERSION RECOVERY (FLAIR); INVERSION RECOVERY; PULSE SEQUENCES; SPINE; 3-DIMENSIONAL IMAGING;
D O I
10.1002/jmri.1880050417
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Fluid-attenuated inversion recovery (FLAIR) is a pulse sequence used for acquiring TO-weighted images of the brain and spine in which the normally high signal intensity of CSF is greatly attenuated. The CSF-suppressed T2-weighted contrast of this technique may be more sensitive to a variety of disorders than that of conventional T2-weighted imaging. The primary disadvantage associated with conventional spin-echo implementations of FLAIR is the relatively limited anatomic coverage that can be achieved in a reasonable imaging time, We developed and optimized a three-dimensional magnetization-prepared rapid gradient-echo (3D MP-RAGE) pulse sequence that combines CSF-suppressed T2-weighted contrast similar to existing FLAIR techniques with anatomic coverage characteristic of 3D imaging. A preliminary evaluation of the new sequence was performed by imaging healthy volunteers and patients with multiple sclerosis.
引用
收藏
页码:463 / 469
页数:7
相关论文
共 21 条
[1]  
Hajnal JV, Bryant DJ, Kasuboskl L, Et al., Use of fluid attenuated inversion recovery (FLAIR) pulse sequences in MRI of the brain, J Comput Assist Tomogr, 16, pp. 841-844, (1992)
[2]  
White SJ, Hajnal JV, Young IR, Bydder GM, Use of fluid‐attenuated inversion‐recovery pulse sequences for imaging the spinal cord, Magn Reson Med, 28, pp. 153-162, (1992)
[3]  
De Coene B, Hajnal JV, Gatehouse P, Et al., MR of the brain using fluid‐attenuated inversion recovery IFWR) pulse sequences, AJNR, 13, pp. 1555-1564, (1992)
[4]  
De Coene B, Hajnal JV, Pennock JM, Bydder GM, MRI of the brain stem using fluid attenuated inversion recovery pulse sequences, Neuroradiology, 35, pp. 327-331, (1993)
[5]  
Thomas DJ, Pennock JM, Hajnal JV, Young IR, Bydder GM, Steiner RE, Magnetic resonance imaging of spinal cord in multiple sclerosis by fluid‐attenuated inversion recovery, Lancet, 341, pp. 593-594, (1993)
[6]  
Hajnal JV, De Coene B, Lewis PD, Et al., High signal regions in normal white matter shown by heavily T2‐weighted CSF nulled IR sequences, J Comput Assist Tomogr, 16, pp. 50-513, (1992)
[7]  
Oatridge A, Hajnal JV, Cowan FM, Baudouin CJ, Young IR, Bydder GM, MRI diffusion‐weighted imaging of the brain: contributions to image contrast from CSF signal reduction, use of long echo time and diffusion effects, Clin Radiol, 47, pp. 82-90, (1993)
[8]  
Bydder GM, Bergin PS, Fish DR, Shorvon SD, Oatridge A, Assessment of the FLAIR pulse sequence in MR Imaging of epllepsy, Radlology, 189, P, (1993)
[9]  
Hajnal JV, Kasuboski L, De Coene B, Young IR, Bydder GM, Imaging of the brain using pre inversion multi echo (PRIME) pulse sequences, Works in progress: Soclety of Magnetic Resonance in Medicine, (1992)
[10]  
den Boer JA, Salverda P, Peters TR, Prevo RL, Multislice turbo‐FLAIR in brain studies of multiple sclerosis, Book of abstracts: Society of Magnetic Resonance in Medicine, (1993)