POTENTIATION OF A MONOAMINE OXIDASE INHIBITOR BY TRYPTOPHAN

被引：153

作者：

GLASSMAN, AH

PLATMAN, SR

机构：

[1] Department of Psychiatry, Albert Einstein College of Medicine

[2] Department of Psychiatry, Columbia University

[3] New York State Psychiatric Institute, NY

来源：

JOURNAL OF PSYCHIATRIC RESEARCH | 1969年 / 7卷 / 02期

关键词：

D O I：

10.1016/0022-3956(69)90013-2

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This double blind study investigated the reported potentiation of an MAO inhibitor by tryptophan. Twenty seriously depressed patients were placed on phenelzine sulfate. Half of these patients received supplements of tryptophan while the remainder received a placebo. Those receiving the tryptophan supplements showed significantly more improvement as measured by a modified version of the Hamilton scale. The possible pathways for the mediation of this tryptophan effect are discussed. © 1969.

引用

页码：83 / +

页数：1

共 24 条

[1]

ASHCROFT GW, 1966, LANCET, V2, P1049

[2] 5-HYDROXYINDOLES IN HUMAN CEREBROSPINAL FLUIDS [J].