NEPHROTIC SYNDROME DURING TREATMENT WITH ALPHA-MERCAPTOPROPIONYLGLYCINE

被引:25
作者
RIZZONI, G
PAVANELLO, L
DUSSINI, N
CHIANDETTI, L
ZACCHELLO, G
机构
关键词
D O I
10.1016/S0022-5347(17)56420-4
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
We report 2 cases of cystinuria in which a nephrotic syndrome developed during treatment with alpha-mercaptopropionylglycine. This syndrome resolved after withdrawal of the drug and it did not recur when the alpha-mercaptopropionylglycine was given again in lower doses. The hypothesis is made that the nephrotic syndrome was dose-related. The alpha-mercaptopropionylglycine must be used in doses <50 mg./kg. per day with regular monitoring of 24-hour urinary protein in cystinuric children.
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页码:381 / 382
页数:2
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