CHARACTERIZATION OF CHOLINESTERASES FROM THE PARASITIC NEMATODE TRICHINELLA-SPIRALIS

被引：11

作者：

DEVOS, T ^{[1
]}

DICK, TA ^{[1
]}

机构：

[1] UNIV MANITOBA,DEPT ZOOL,WINNIPEG R3T 2N2,MANITOBA,CANADA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1992年 / 103卷 / 01期

关键词：

D O I：

10.1016/0742-8413(92)90241-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Trichinella cholinesterases occur in multiple molecular forms which differ in size, kinetics, activity with butyrylthiocholine, and effects of inhibitors. 2. The 5.3 and 13S forms identified in Trichinella extracts are also found in C. elegans and other nematodes but the 7S form which occurs in other nematodes was absent from Trichinella detergent extracts. Differences in kinetic and inhibition properties among nematode species were also evident. 3. The level of cholinesterases in excretory/secretory products is low. 4. Trichinella cholinesterases did not elicit a detectable antibody response in mice.

引用

页码：129 / 134

页数：6

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