AUTOSOMAL DOMINANT MICROCEPHALY

被引：44

作者：

HASLAM, RHA

SMITH, DW

机构：

[1] UNIV CALGARY, DIV PEDIAT, CALGARY T2N 1N4, ALBERTA, CANADA

[2] UNIV WASHINGTON, SEATTLE, WA 98195 USA

来源：

JOURNAL OF PEDIATRICS | 1979年 / 95卷 / 05期

关键词：

D O I：

10.1016/S0022-3476(79)80714-3

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Four families with autosomal dominant microcephaly are reported. Although the phenotype is nondistinctive, several patients had receding or small foreheads, upslanted palpebral fissues, or prominent ears. The degree of intellectual dysfunction is not as severe as that recorded in autosomal recessive microcephaly. It would appear that autosonal dominant microcephaly is more common than previously recorded, and that head circumference measurements of siblings and parents of affected patients should become a part of the initial investigation. © 1979 The C. V. Mosby Company.

引用

页码：701 / 705

页数：5