MULTI-FACTORIAL SPECIFICATION OF VIRUS-HOST INTERACTIONS - STUDIES WITH STRAINS OF VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS IN MICE

被引：12

作者：

WALDER, R ^{[1
]}

BRADISH, CJ ^{[1
]}

机构：

[1] MICROBIOL RES ESTAB,SALISBURY SP4 0JG,WILTSHIRE,ENGLAND

来源：

JOURNAL OF GENERAL VIROLOGY | 1979年 / 44卷 / AUG期

关键词：

D O I：

10.1099/0022-1317-44-2-373

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Mice of different ages were infected i.p. or i.c. by 23 different strains of VEE virus. The course of the virus host interaction was specified in terms of the efficiency of infection, the outcome of infection as lethality or protection and the survival time. These separately quantifiable features all showed several host-maturation events that combine to provide a multifactorial specification of virus-strains and host-responses. This base-line for correlations with the responses of principal hosts (equidae and man) may be expanded to test correlations with the antigenic or in vitro characteristics of virus-strains.

引用

页码：373 / 382

页数：10

共 15 条

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