INHALATION MR LYMPHOGRAPHY - A NEW METHOD FOR SELECTIVE ENHANCEMENT OF THE LUNG HILAR AND MEDIASTINAL LYMPH-NODES

被引：6

作者：

OKUHATA, Y

XIA, TY

URAHASHI, S

机构：

[1] Department of Radiology, Nihon University School of Medicine, Tokyo

来源：

MAGNETIC RESONANCE IMAGING | 1994年 / 12卷 / 08期

关键词：

MR IMAGING; LYMPH NODES; INHALATION; IRON COLLOID; CONTRAST ENHANCEMENT;

D O I：

10.1016/0730-725X(94)90077-5

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

On MR lymphography, a new approach to the lung hilar and mediastinal nodes was developed in an animal model. Five rabbits were made to inhale iron colloid (cideferron) that was nebulized to aerosol. Two days after inhalation of the agent, the mediastinal lymph nodes decreased in signal on SE 2000/30 and SE 2000/60 images and proved to have iron on histological evaluation, whereas the popliteal nodes did not have any iron. Experimental results indicate that inhalational administration can deliver the agent to the pulmonary lymphatic system and has the potential of lung hilar and mediastinal MR lymphography.

引用

页码：1135 / 1138

页数：4

共 14 条

[1]

Stitik, DiSantis, Lung cancer staging, Semin. Roentgenol., 25, pp. 34-44, (1990)

[2]

Naruke, Goya, Tsuchiya, Suemasu, Prognosis and survival in resected lung carcinoma based on the new international staging system, J. Thorac. Cardiovasc. Surg., 96, pp. 440-447, (1988)

[3]

Libshitz, Computed tomography in bronchogenic carcinoma, Semin. Roentgenol., 25, pp. 64-72, (1990)

[4]

Stiglbauer, Schurawitzki, Klepetko, Kramer, Schratter, Tscholakoff, Eckersberger, Contrast-enhanced MRI for the staging of bronchogenic carcinoma: Comparison with CT and histopathologic staging — Preliminary results, Clin. Radiol., 44, pp. 293-298, (1991)

[5]

Weissleder, Elizondo, Wittenberg, Lee, Josephson, Brady, Ultrasmall superparamagnetic iron oxide: An intravenous contrast agent for assessing lymph nodes with MR imaging, Radiology, 175, pp. 494-498, (1990)

[6]

Weissleder, Elizondo, Josephson, Compton, Fretz, Stark, Ferrucci, Experimental lymph node metastases: Enhanced detection with MR lymphography, Radiology, 171, pp. 835-839, (1989)

[7]

Okuhata, Urahashi, Kamata, Arimizu, A preliminary study on MR lymphography with iron chondroitin sulfate colloid, Nippon Igaku Houshasen Gakkai Zasshi, 50, pp. 671-673, (1990)

[8]

Okuhata, An experimental study on MR lymphography with various iron colloid agents, Nippon Igaku Houshasen Gakkai Zasshi, 52, pp. 1148-1160, (1992)

[9]

Taupitz, Wagner, Hamm, Binder, Pfefferer, Interstitial MR lymphography with iron oxide particles: Results in tumor-free and VX2 tumor-bearing rabbits, AJR, 161, pp. 193-200, (1993)

[10]

Okuhata, Xia, Urahashi, Arimizu, MR lymphography: First application to human, Nippon Igaku Houshasen Gakkai Zasshi, 54, pp. 410-412, (1994)

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