TRANSCUTANEOUS NITROGLYCERIN IN THE TREATMENT OF ERECTILE DYSFUNCTION IN SPINAL-CORD INJURED

被引：16

作者：

SONKSEN, J

BIERINGSORENSEN, F

机构：

[1] Department of Urology, Copenhagen, DK-2100

[2] Centre for Spinal Cord Injured, Rigshospitalet, University of Copenhagen, Copenhagen, DK-2100

来源：

PARAPLEGIA | 1992年 / 30卷 / 08期

关键词：

SPINAL CORD INJURY; IMPOTENCE; NITROGLYCERIN;

D O I：

10.1038/sc.1992.114

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We have tested the erectile effect of penile applicated nitroglycerin plasters (Transiderm-Nitro 10 mg/24 hours) in 17 spinal cord injured men, who had responded to intracavernous papaverine injections with erections sufficient for vaginal penetration. The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men. A total of 5 men reported an erectile response sufficient for vaginal penetration after using nitroglycerin plasters at home. All 5 preferred to continue with this noninvasive treatment compared to papaverine injections. Our results indicate that men with spinal cord injury who need doses larger than 15 mg papaverine to obtain erection sufficient for vaginal penetration will not achieve this with nitroglycerin plasters. We suggest that this noninvasive treatment should be tested on spinal cord injured men before injection therapy is initiated.

引用

页码：554 / 557

页数：4

共 13 条

[1]

Beretta G., Zanollo A., Fanciullacci F., Catanzaro F., Intracavernous injection of papaverin in paraplegic males, Acta Europaea Fertilitatis, 17, pp. 283-284, (1986)

[2]

Bodner D.R., Lindan R., Leffler E., Kursh E.D., Resnick M.I., The application of intracavernous injection of vasoactive medications for erection in men with spinal cord injury, 1 Ural, 38, pp. 310-311, (1987)

[3]

Sidi A.A., Cameron J.S., Dykstra D.D., Reinberg Y., Lange P.H., Vasoactive intracavernous pharmacotherapy for the treatment of erectile impotence in men with spinal cord injury, 1 Ural, 138, pp. 539-542, (1987)

[4]

Virag R., Sussman H., Floresco J., Shoukry K., Late results on the treatment of neurogenic impotence by selfintracavernous injection (SICI) of vasoactive drugs, World 1 Ural, 5, pp. 166-170, (1987)

[5]

Lloyd L.K., Richards J.S., Intracavernous pharmacotherapy for management of erectile dysfunction in spinal cord injury, Paraplegia, 27, pp. 457-464, (1989)

[6]

Wyndaele J.J., De Meyer J.M., De Sy W.A., Claessens H., Intracavernous injection of vasoactive drugs, an alternative for treating impotence in spinal cord injury patients, Paraplegia, 24, pp. 271-275, (1986)

[7]

Jiinemann K., Aiken P., Pharmacotherapy of erectile dysfunction: A review, Znt 1 Impotence Res, 1, pp. 71-93, (1989)

[8]

Claes H., Baert L., Trancutaneous nitroglycerin therapy in the treatment of impotence, Ural Znt, 44, pp. 309-312, (1989)

[9]

Owen J.A., Saunders F., Harris C., Et al., Topical nitroglycerin: A potential treatment for impotence, 1 Ural, 141, pp. 546-548, (1989)

[10]

Meyhoff H.H., Rosenkilde P., Bodker A., Non-invasive management of impotence with transcutaneous nitroglycerin, Br 1 Ural, 69, pp. 88-90, (1992)

← 1 2 →