VIRULENCE OF 2 STREPTOCOCCUS-PYOGENES STRAINS (TYPES M1 AND M3) ASSOCIATED WITH TOXIC-SHOCK-LIKE SYNDROME DEPENDS ON AN INTACT MRY-LIKE GENE

被引：20

作者：

PEREZCASAL, JF ^{[1
]}

DILLON, HF ^{[1
]}

HUSMANN, LK ^{[1
]}

GRAHAM, B ^{[1
]}

SCOTT, JR ^{[1
]}

机构：

[1] EMORY UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL,ATLANTA,GA 30322

来源：

INFECTION AND IMMUNITY | 1993年 / 61卷 / 12期

关键词：

D O I：

10.1128/IAI.61.12.5426-5430.1993

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The major virulence factor of Streptococcus pyogenes, the M protein, is positively regulated at the transcriptional level by mry in the M type 6 strain studied. We show here that in two S. pyogenes strains isolated from cases of toxic-shock-like syndrome, a type M1 strain and a type M3 strain, an mry-like gene is also required for resistance to phagocytosis.

引用

页码：5426 / 5430

页数：5

共 21 条

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