DIASTEREOSELECTIVE AND ENANTIOSELECTIVE GLYOXYLATE-ENE REACTION CATALYZED BY NEW CLASS OF BINAPHTHOL-DERIVED TITANIUM COMPLEX

被引：66

作者：

TERADA, M ^{[1
]}

MOTOYAMA, Y ^{[1
]}

MIKAMI, K ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT CHEM TECHNOL,MEGURO KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)73470-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereo- and enantioselective carbony-ene reaction of glyoxylate (2) with trisubstituted olefins (3) catalyzed by chiral titanium complexes (1a), derived from 6,6'-dibromo-1,1'-bi-2-naphthol and disopropoxytitanium dihalides, is found to provide syn-diastereomers exclusively along with a high level of enantioselectivity.

引用

页码：6693 / 6696

页数：4

共 16 条

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