PURIFICATION OF A GLYCOPROTEIN EXCRETED BY TRYPANOSOMA-CRUZI TO INCREASE THE PERMEABILITY OF THE HOST-CELL MEMBRANE

被引：5

作者：

CASTANYS, S ^{[1
]}

GAMARRO, F ^{[1
]}

RUIZPEREZ, LM ^{[1
]}

OSUNA, A ^{[1
]}

机构：

[1] UNIV GRANADA,FAC SCI,DEPT PARASITOL,E-18001 GRANADA,SPAIN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 166卷 / 02期

关键词：

D O I：

10.1016/0006-291X(90)90871-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During invasion of the prospective host cell, metacyclic forms of Trypanosoma cruzi render the membrane of HeLa cells permeable to the alpha-sarcin toxin, by excreting a glycoprotein with N-acetyl-D-glucosamine residues. The molecular weight of the glycoprotein is 64,000 dalton and its isoelectric point is 4.8. © 1990.

引用

页码：736 / 742

页数：7

共 28 条

[1] PRESENCE OF TRYPANOSOMA-CRUZI ANTIGEN ON THE SURFACE OF BOTH INFECTED AND UNINFECTED CELLS IN TISSUE-CULTURE [J].

ABRAHAMSOHN, IA ;

KLOETZEL, JK .

PARASITOLOGY, 1980, 80 (FEB) :147-&

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3]

BRAVO R, 1982, J MOL BIOL, V159, P121

[4]

CASTANYS S, 1984, PARASITOLOGY, V70, P433

[5]

COLLI W, 1984, NEW APPROACHES VACCI, P418

[6]

CONTRERAS A, 1979, J VIROL, V22, P591

[7]

DESAFILHO SA, 1984, ACTA TROP, V41, P109

[8]

DOSSANTOS RR, 1981, CLIN EXP IMMUNOL, V44, P349

[9]

DOSSANTOS RR, 1980, CLIN EXP IMMUNOL, V40, P36

[10]

EILMAN Y, 1985, EXP PARASITOL, V59, P161

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