SYNTHESIS OF VINCA ALKALOIDS AND RELATED-COMPOUNDS .44. SYNTHESIS OF TRIFLUORO-APOVINCAMINIC ACID ESTER

被引：6

作者：

INCZE, M

SOTI, F

KARDOSBALOGH, Z

KAJTARPEREDY, M

SZANTAY, C

机构：

[1] Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest, H-1525

来源：

ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 06期

关键词：

D O I：

10.1002/ardp.19903230604

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Via the intermediate iminium salt 8 the 21,21,21‐trifluoro‐apovincaminic acid ethyl ester (2), a derivative of CAVINTONR (1) was synthesized. The pharmacological effect of 2 changed dramatically compared with the parent compound. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

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页码：331 / 333

页数：3

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