CONFORMATIONAL-ANALYSIS OF ERYTHROMYCIN A DERIVATIVES - A PREDICTIVE METHOD USING NMR CHEMICAL-SHIFT AND COUPLING-CONSTANT DATA

被引：17

作者：

EVERETT, JR ^{[1
]}

HATTON, IK ^{[1
]}

TYLER, JW ^{[1
]}

机构：

[1] BEECHAM PHARMACEUT,CHEMOTHERAPEUT RES CTR,BROCKHAM PK,BETCHWORTH RH3 7AJ,SURREY,ENGLAND

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 1990年 / 28卷 / 02期

关键词：

!sup]13[!/sup]C NMR; !sup]1[!/sup]H NMR; Conformational analysis; Erythromycin A derivatives;

D O I：

10.1002/mrc.1260280205

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1H and 13C NMR chemical shift data and 3J(H,H) values can be used to predict the conformational blend of new members of a series of erythromycin A derivatives in CDCI3 solution. Copyright © 1990 John Wiley & Sons, Ltd.

引用

页码：114 / 118

页数：5

共 23 条

[1] Davies J., UNPUB
[2] CONFORMATIONAL FLEXIBILITY OF ERYTHRONOLIDE-B, 14-MEMBERED AGLYCON RING OF ERYTHROMYCINS
EGAN, RS
MARTIN, JR
PERUN, TJ
MITSCHER, LA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (16) : 4578 - 4583
[3] CONFORMATION OF ERYTHRONOLIDE, 14-MEMBERED AGLYCONE RING OF ERYTHROMYCIN ANTIBIOTICS
EGAN, RS
PERUN, TJ
MARTIN, JR
MITSCHER, LA
[J]. TETRAHEDRON, 1973, 29 (17) : 2525 - 2538
[4] EGAN RS, 1971, THESIS U ILLINOIS ME
[5] THE CONFORMATIONAL-ANALYSIS OF 3 DERIVATIVES OF ERYTHROMYCIN-A - (9S)-9-HYDROXY-9-DEOXOERYTHROMYCIN-A, (9S)-9,11-O-ISOPROPYLIDENE-9-DEOXOERYTHROMYCIN-A, AND (9S)-ERYTHROMYCYLAMINE-A BY NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY AND MOLECULAR MODELING
EVERETT, JR
TYLER, JW
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1988, (03): : 325 - 337
[6] AN ANALYSIS OF THE H-1 AND C-13 NMR-SPECTRA OF ERYTHROMYCIN-A USING TWO-DIMENSIONAL METHODS
EVERETT, JR
TYLER, JW
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1985, (12): : 2599 - 2603
[7] NOVEL CONFORMATIONS OF ERYTHROMYCIN ANTIBIOTICS - THE CONFORMATIONAL-ANALYSIS OF ERYTHROMYCIN-A AND (9S)-9-HYDROXY-9-DEOXOERYTHROMYCIN A BY NMR-SPECTROSCOPY
EVERETT, JR
TYLER, JW
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (11) : 815 - 816
[8] THE CONFORMATIONAL-ANALYSIS OF ERYTHROMYCIN-A
EVERETT, JR
TYLER, JW
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1987, (11): : 1659 - 1667
[9] EVERETT JR, 1989, IN PRESS J CHEM S P2
[10] HARRIS DR, 1965, TETRAHEDRON LETT, P679

← 1 2 3 →