INFLUENCE OF SITE OF EXPRESSION ON THE FETAL GAMMA-DELTA T-CELL RECEPTOR REPERTOIRE

被引：21

作者：

KYES, S ^{[1
]}

PAO, W ^{[1
]}

HAYDAY, A ^{[1
]}

机构：

[1] YALE UNIV,DEPT IMMUNOBIOL,NEW HAVEN,CT 06511

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 17期

关键词：

D O I：

10.1073/pnas.88.17.7830

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The sequences of productive T-cell gamma/delta receptor transcripts were compared in different murine fetal tissues. Differences from tissue to tissue suggest that the sequence repertoires are at least in part the products of selection, presumably through interaction of T cells bearing the gamma-delta receptor with fetal self-ligands.

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页码：7830 / 7833

页数：4

相关论文

共 23 条

[1]

ARSANOW DM, 1988, CELL, V55, P837

[2] DISTINCT ANTIGEN RECEPTOR REPERTOIRES OF 2 CLASSES OF MURINE EPITHELIUM-ASSOCIATED T-CELLS [J].

ASARNOW, DM ;

GOODMAN, T ;

LEFRANCOIS, L ;

ALLISON, JP .

NATURE, 1989, 341 (6237) :60-62

[3] EXTRATHYMIC ORIGIN OF INTESTINAL INTRAEPITHELIAL LYMPHOCYTES BEARING T-CELL ANTIGEN RECEPTOR-GAMMA-DELTA [J].

BANDEIRA, A ;

ITOHARA, S ;

BONNEVILLE, M ;

BURLENDEFRANOUX, O ;

MOTASANTOS, T ;

COUTINHO, A ;

TONEGAWA, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (01) :43-47

[4]

BURNET FM, 1959, CLONAL SELECTION THE

[5] DEVELOPMENTALLY REGULATED FETAL THYMIC AND EXTRATHYMIC T-CELL RECEPTOR-GAMMA-DELTA GENE-EXPRESSION [J].

CARDING, SR ;

KYES, S ;

JENKINSON, EJ ;

KINGSTON, R ;

BOTTOMLY, K ;

OWEN, JJT ;

HAYDAY, AC .

GENES & DEVELOPMENT, 1990, 4 (08) :1304-1315

[6]

ELLIOTT JF, 1988, NATURE, V331, P627

[7] THE DEVELOPMENT AND FUNCTION OF GAMMA-DELTA T-CELLS [J].

HAAS, W ;

KAUFMAN, S ;

MARTINEZA, C .

IMMUNOLOGY TODAY, 1990, 11 (10) :340-343

[8] ORIGIN OF THY-1+ DENDRITIC EPIDERMAL-CELLS OF ADULT MICE FROM FETAL THYMIC PRECURSORS [J].

HAVRAN, WL ;

ALLISON, JP .

NATURE, 1990, 344 (6261) :68-70

[9] DEVELOPMENTALLY ORDERED APPEARANCE OF THYMOCYTES EXPRESSING DIFFERENT T-CELL ANTIGEN RECEPTORS [J].

HAVRAN, WL ;

ALLISON, JP .

NATURE, 1988, 335 (6189) :443-445

[10] SELECTION OF GAMMA-DELTA-T-CELLS WITH CANONICAL T-CELL ANTIGEN RECEPTORS IN FETAL THYMUS [J].

ITOHARA, S ;

TONEGAWA, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (20) :7935-7938