MATERNAL PLASMA-CONCENTRATIONS OF MAGNESIUM, CALCIUM, ZINC AND COPPER IN NORMAL AND PATHOLOGICAL PREGNANCIES

被引：79

作者：

BORELLA, P

SZILAGYI, A

THAN, G

CSABA, I

GIARDINO, A

FACCHINETTI, F

机构：

[1] PECS MED SCH, DEPT OBSTET & GYNECOL, H-7643 PECS, HUNGARY

[2] UNIV MODENA, IST OSTET & GINECOL, I-41100 MODENA, ITALY

来源：

SCIENCE OF THE TOTAL ENVIRONMENT | 1990年 / 99卷 / 1-2期

关键词：

D O I：

10.1016/0048-9697(90)90212-D

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 [工学]; 0830 [环境科学与工程];

摘要：

In this study, plasma levels of magnesium, calcium, zinc and copper were simultaneously determined in pregnancies complicated by either abortion, intrauterine growth retardation (IUGR), diabetes or EPH (edema, proteinuria, hypertension) gestosis. The levels of the four cations in non-pregnant women and in healthy, pregnant women were also determined. Compared with controls, a significant decrease in magnesium, with increase of the Ca/Mg ratio, was found in spontaneous abortions, but not when patients had a successful continuation of pregnancy. In EPH gestosis, total calcium was reduced, with a significant decrease of the plasma Ca/Mg ratio. A slight, but significant, increase in plasma zinc was observed in women affected by either diabetes or IUGR, probably as a result of reduced zinc uptake by the fetus. In addition, higher copper levels were found in the pathologies studied, with the exception of missed abortions. The possible role of an altered Ca/Mg ratio homeostasis in relation to gestational pathologies is discussed. © 1990.

引用

页码：67 / 76

页数：10

共 44 条

[1]

Adeniyi, The implications of hypozincemia in pregnancy, Acta Obstet. Gynecol. Scand., 66, pp. 579-587, (1987)

[2]

Ajayi, Serum magnesium concentration in premenopausal, menopausal women, during normal and EPH-gestosis pregnancy and the effect of diuretic therapy in EPH-gestosis, Magnesium Bull., 10, pp. 72-76, (1988)

[3]

Altura, Altura, Carella, Magnesium deficiency-induced spasms of umbilical vessels: relation to preeclampsia, hypertension, growth retardation, Science, 221, pp. 376-377, (1983)

[4]

Belizan, Villar, Zalazar, Rojas, Chan, Bryce, Preliminary evidence of the effect of calcium supplementation on blood pressure in normal pregnant women, Am. J. Obstet. Gynecol., 146, pp. 175-180, (1983)

[5]

Belizan, Villar, Repke, The relationship between calcium intake and pregnancy-induced hypertension: up-to-date evidence, Am. J. Obstet. Gynecol., 158, pp. 898-902, (1988)

[6]

Bodgen, Thind, Lauria, Caterini, Maternal and cord blood metal concentrations and low birth weight - a case control study, Am. J. Clin. Nutr., 31, pp. 1181-1187, (1978)

[7]

Boston, Beauchene, Cruikshank, Erythrocyte and plasma magnesium during teenage pregnancy: Relationship with blood pressure and pregnancy-induced hypertension, Obstet. Gynecol., 73, pp. 169-174, (1989)

[8]

Campbell-Brown, Ward, Haines, North, Abraham, McFadyen, Zinc and copper in Asian pregnancies - is there evidence for a nutritional deficiency?, Br. J. Obstet. Gynaecol., 92, pp. 875-885, (1985)

[9]

Cherry, Bennett, Bazzano, Johnson, Fosmire, Batson, Plasma zinc in hypertension/toxemia and other reproductive variables in adolescent pregnancy, Am. J. Clin. Nutr., 34, pp. 2367-2375, (1981)

[10]

Chueca, Serrano, Carrasco, Chueca, Correlation between calcium and magnesium in plasma or serum?, Clin. Chem., 33, pp. 304-305, (1987)

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