POPULATION-GENETICS AND FORENSIC EFFICIENCY DATA OF 4 AMPFLPS

被引：115

作者：

RAND, S ^{[1
]}

PUERS, C ^{[1
]}

SKOWASCH, K ^{[1
]}

WIEGAND, P ^{[1
]}

BUDOWLE, B ^{[1
]}

BRINKMANN, B ^{[1
]}

机构：

[1] FBI ACAD,CTR FORENS SCI RES & TRAINING,QUANTICO,VA 22135

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1992年 / 104卷 / 06期

关键词：

AMPFLPS; PCR; ALLELE FREQUENCIES; DISCRIMINATION INDEX; HARDY-WEINBERG EQUILIBRIUM;

D O I：

10.1007/BF01369552

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Family studies were carried out in a population sample from north west Germany using 4 amplifiable VNTR polymorphic systems D1S80 (MCT118), ApoB, D17S30 (YNZ22) and COL2A1. Separation was carried out in polyacrylamide gels and visualised using silver staining. In family studies (n = 30) no evidence of new mutations was found. The population study of unrelated individuals (mothers and putative fathers) showed that all 4 systems were highly polymorphic and similar to other population studies. The combined exclusion chance was calculated to be approximately 99% and the combined discrimination index 1.5.10(-4). The Hardy-Weinberg equilibrium was checked by forming groups of alleles and no significant deviations could be found in all systems.

引用

页码：329 / 333

页数：5

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