AGENTS THAT AFFECT CALCIUM INFLUX CAN CHANGE CYCLIC-NUCLEOTIDE LEVELS IN CULTURED CHICK PINEAL CELLS

被引：27

作者：

ZATZ, M

机构：

[1] Section on Biochemical Pharmacology, Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, Maryland

来源：

BRAIN RESEARCH | 1992年 / 583卷 / 1-2期

关键词：

MELATONIN; CIRCADIAN RHYTHM;

D O I：

10.1016/S0006-8993(10)80039-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Previous experiments examined interactions among the effects of cyclic AMP and calcium-related agents on melatonin output by cultured chick pineal cells, and suggested that changes in calcium influx might act through cyclic AMP. Here, effects of calcium-related agents and manipulations on cyclic AMP (and cyclic GMP) levels are demonstrated directly. These effects support a role for cyclic AMP (but not cyclic GMP) in the effects of changes in calcium influx on melatonin production by these cells.

引用

页码：304 / 307

页数：4

共 27 条

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