EFFECTS OF RECOMBINANT ALPHA-INTERFERON ON CHRONIC ACTIVE HEPATITIS-B - PRELIMINARY-RESULTS

被引：5

作者：

BAYRAKTAR, Y ^{[1
]}

UZUNALIMOGLU, B ^{[1
]}

ARSLAN, S ^{[1
]}

KOSEOGLU, T ^{[1
]}

KAYHAN, B ^{[1
]}

TELATAR, H ^{[1
]}

机构：

[1] HACETTEPE UNIV HOSP,SCH MED,DEPT PATHOL,ANKARA,TURKEY

来源：

GUT | 1993年 / 34卷 / 02期

关键词：

D O I：

10.1136/gut.34.2_Suppl.S101

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This paper presents the preliminary results of a study designed to evaluate the effects of alpha interferon in chronic hepatitis B. After six months' treatment with interferon alfa-2b (5 million units (MU), three times weekly) 15 of 25 (60%) patients achieved seroconversion of hepatitis B e antigen, 17 (68%) normalised alanine aminotransferase (ALT) activity, and 15 (60%) showed a decrease in the inflammatory reaction on liver histology. No seroconversions occurred in the control group (n=10), and none of the control patients achieved a normal ALT or showed a reduction in the inflammatory reaction. Adverse effects were experienced by most patients who received interferon but none warranted stopping the treatment.

引用

页码：S101 / S101

页数：1