MECHANISM OF ALPHA-CHYMOTRYPSIN-CATALYZED HYDROLYSIS OF AMIDES - PH DEPENDENCE OF KC AND KM - KINETIC DETECTION OF AN INTERMEDIATE

被引：84

作者：

FERSHT, AR

REQUENA, Y

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1971年 / 93卷 / 25期

关键词：

D O I：

10.1021/ja00754a066

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：7079 / +

页数：1

共 45 条

[1] ON THE INTERPRETATION OF THE PH VARIATION OF THE MAXIMUM INITIAL VELOCITY OF AN ENZYME-CATALYZED REACTION [J].

ALBERTY, RA ;

MASSEY, V .

BIOCHIMICA ET BIOPHYSICA ACTA, 1954, 13 (03) :347-353

[2] The preparation of semicarbazide [J].

Audrieth, LF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1930, 52 :1250-1251

[3] SPECIFICITY OF ALPHA-CHYMOTRYPSIN - DIPEPTIDE SUBSTRATES [J].

BAUMANN, WK ;

BIZZOZERO, SA ;

DUTLER, H .

FEBS LETTERS, 1970, 8 (05) :257-+

[4] ALKALINE PH DEPENDENCE OF CHYMOTRYPSIN REACTIONS - POSTULATION OF A PH-DEPENDENT INTRAMOLECULAR COMPETITIVE INHIBITION [J].

BENDER, ML ;

GIBIAN, MJ ;

WHELAN, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 56 (03) :833-&

[5] CURRENT STATUS OF ALPHA-CHYMOTRYPSIN MECHANISM [J].

BENDER, ML ;

KEZDY, FJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (18) :3704-&

[6] CORRELATION OF PH (PD) DEPENDENCE + STEPWISE MECHANISM OF ALPHA-CHYMOTRYPSIN-CATALYZED REACTIONS [J].

BENDER, ML ;

CLEMENT, GE ;

HECK, HD ;

KEZDY, FJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (18) :3680-&

[7] DETERMINATION OF CONCENTRATION OF HYDROLYTIC ENZYME SOLUTIONS - ALPHA-CHYMOTRYPSIN TRYPSIN PAPAIN ELASTASE SUBTILISIN AND ACETYLCHOLINESTERASE [J].

BENDER, ML ;

BEGUECAN.ML ;

BLAKELEY, RL ;

BRUBACHER, LJ ;

FEDER, J ;

GUNTER, CR ;

KEZDY, FJ ;

KILLHEFFER, JV ;

MARSHALL, TH ;

MILLER, CG ;

ROESKE, RW ;

STOOPS, JK .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (24) :5890-+

[8] ON INTERACTION OF ACTIVE SITE OF ALPHA-CHYMOTRYPSIN WITH CHROMOPHORES - PROFLAVIN BINDING AND ENZYME CONFORMATION DURING CATALYSIS [J].

BERNHARD, SA ;

LEE, BF ;

TASHJIAN, ZH .

JOURNAL OF MOLECULAR BIOLOGY, 1966, 18 (03) :405-&

[9] MECHANISM OF AMINOLYSIS OF METHYL FORMATE [J].

BLACKBURN, GM ;

JENCKS, WP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (10) :2638-+

[10] ROLE OF A BURIED ACID GROUP IN MECHANISM OF ACTION OF CHYMOTRYPSIN [J].

BLOW, DM ;

BIRKTOFT, JJ ;

HARTLEY, BS .

NATURE, 1969, 221 (5178) :337-&

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