DELETION-20Q IN ASSOCIATION WITH PHILADELPHIA-CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC-LEUKEMIA - A REPORT OF 2 CASES

被引：12

作者：

HOLLINGS, PE ^{[1
]}

BENJES, SM ^{[1
]}

ROSMAN, I ^{[1
]}

FITZGERALD, PH ^{[1
]}

机构：

[1] CHRISTCHURCH HOSP,CYTOGENET & MOLEC ONCOL UNIT,CHRISTCHURCH,NEW ZEALAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 79卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)00068-M

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic deletions involving the long arm of chromosome 20 are thought to be characteristic of myeloid disorders. We report clinical and cytogenetic observations of two adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia: one with a smaller 20q deletion that was the sole cytogenetic abnormality in a persisting remission clone, the other with a larger 20q deletion that was a late addition to the leukemic clone at disease relapse following allogeneic bone marrow transplantation.

引用

页码：32 / 35

页数：4

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