EFFECT OF BACLOFEN ON ALPHA-FLUPENTHIXOL-INDUCED CATALEPSY IN RAT

被引：7

作者：

DAVIES, JA

WILLIAMS, J

机构：

[1] Department of Pharmacology, Welsh National School of Medicine, Cardiff, Heath Park

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 1978年 / 62卷 / 02期

关键词：

D O I：

10.1111/j.1476-5381.1978.tb08460.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

α‐Flupenthixol (α‐FPT; 0.2 mg/kg i.p.) when administered to rats produced catalepsy. Baclofen (10 mg/kg i.p.) given 30 min after α‐FPT had a biphasic effect on the catalepsy. Initially there was a potentiation of the effect, followed by a significant attenuation of the degree of catalepsy. Possible mechanisms of action are discussed. 1978 British Pharmacological Society

引用

页码：303 / 305

页数：3

共 12 条

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[2]

CARLSSON A, 1963, ACTA PHARMACOL TOX, V20, P140

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