OPIOID-PEPTIDES IN MICELLAR SYSTEMS - CONFORMATIONAL-ANALYSIS BY CD AND BY ONE-DIMENSIONAL AND 2-DIMENSIONAL H-1-NMR SPECTROSCOPY

被引：19

作者：

ZETTA, L ^{[1
]}

CONSONNI, R ^{[1
]}

DEMARCO, A ^{[1
]}

LONGHI, R ^{[1
]}

MANERA, E ^{[1
]}

VECCHIO, G ^{[1
]}

机构：

[1] CNR,IST CHIM ORMONI,I-20131 MILAN,ITALY

来源：

BIOPOLYMERS | 1990年 / 30卷 / 9-10期

关键词：

D O I：

10.1002/bip.360300905

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

beta-Endorphin has been studied in SDS micelles by one- and two-dimensional nmr spectroscopy (1D and 2D nmr), and to explore the influence of peptide length and composition on the polypeptide structure, the investigation was extended to a number of fragments. The nmr results are compared with those obtained from CD experiments and discussed in terms of a secondary structure that involves the central region of beta-endorphin.

引用

页码：899 / 909

页数：11

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