A PHYSICAL MAP OF A 1.3-MB REGION ON THE LONG ARM OF CHROMOSOME-12, SPANNING THE GLI AND LRP LOCI

被引：20

作者：

FORUS, A ^{[1
]}

MYKLEBOST, O ^{[1
]}

机构：

[1] NORWEGIAN RADIUM HOSP,INST CANC RES,DEPT TUMOR BIOL,N-0310 OSLO,NORWAY

来源：

GENOMICS | 1992年 / 14卷 / 01期

关键词：

D O I：

10.1016/S0888-7543(05)80292-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have used pulsed-field gel electrophoresis to construct a long-range restriction map spanning more than 1.3 million bp of the q13-q14 segment of chromosome 12. Within this region lie the genes coding for the gli oncogene and the low-density lipoprotein receptor-related protein (LRP). The distance between the genes is about 200-300 kb. We also observe a methylation-free island 3′ to the LRP gene. © 1992 Academic Press, Inc. All rights reserved.

引用

页码：117 / 120

页数：4

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