DISSEMINATED COCCIDIOIDOMYCOSIS ASSOCIATED WITH EXTREME EOSINOPHILIA

被引：34

作者：

HARLEY, WB ^{[1
]}

BLASER, MJ ^{[1
]}

机构：

[1] VANDERBILT UNIV, MED CTR,SCH MED,DEPT MED,DIV INFECT DIS, A3310 MED CTR N, NASHVILLE, TN 37232 USA

来源：

CLINICAL INFECTIOUS DISEASES | 1994年 / 18卷 / 04期

关键词：

D O I：

10.1093/clinids/18.4.627

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Primary coccidioidomycosis is frequently accompanied by eosinophilia in the range of 5%-10% of the peripheral white blood cell count. Dissemination of Coccidioides immitis to organs such as skin, bone, joints, and CNS usually is associated with risk factors such as sex (male), race (non-Caucasian), pregnancy, and immunosuppression. We report a case of coccidioidomycosis in an otherwise healthy African-American man with 72% eosinophilia who had dissemination to the skin, and we review cases in the literature of disseminated disease associated with eosinophilia. Marked eosinophilia may be an important early clue that dissemination of coccidioidomycosis has occurred.

引用

页码：627 / 629

页数：3

共 18 条

[1]

AMPEL NM, 1989, REV INFECT DIS, V11, P897

[2] UNUSUAL SYNDROMES OF COCCIDIOIDOMYCOSIS - DIAGNOSTIC AND THERAPEUTIC CONSIDERATIONS - REPORT OF 10 CASES AND REVIEW OF ENGLISH LITERATURE [J].