INDIUM-ANTIMONIDE (INSB) FOCAL-PLANE ARRAY (FPA) DETECTION FOR NEAR-INFRARED IMAGING MICROSCOPY

被引:83
作者
TREADO, PJ [1 ]
LEVIN, IW [1 ]
LEWIS, EN [1 ]
机构
[1] UNIV PITTSBURGH, DEPT CHEM, PITTSBURGH, PA 15260 USA
关键词
D O I
10.1366/0003702944924899
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
Near-infrared spectroscopy is a sensitive, noninvasive method for chemical analyses, and its integration with imaging technologies represents a potent tool for the study of a wide range of materials. In this communication the use of an indium antimonide (InSb) multichannel imaging detector for near-infrared absorption spectroscopic microscopy is described. In particular, a 128 x 128 pixel InSb staring array camera has been combined with a refractive optical microscope and an acousto-optic tunable filter (AOTF) to display chemically discriminative, spatially resolved, vibrational spectroscopic images of biological and polymeric systems. AOTFs are computer-controlled bandpass filters that provide high speed, random wavelength access, wide spectral coverage, and high spectral resolution. Although AOTFs inherently have a wide range of spectroscopic applications, we apply this technology to NIR absorption microscopy between 1 and 2.5 mum. The spectral interval is well matched to the optical characteristics of both the NIR refractive microscope and the AOTF, thereby providing near-diffraction-limited performance with a practical spatial resolution of 1 to 2 mum. Design principles of this novel instrumentation and representative applications of the technique are presented for various model systems.
引用
收藏
页码:607 / 615
页数:9
相关论文
共 30 条
  • [1] ABRAMOWITZ MJ, 1993, AM LAB, V25, P66
  • [2] BAILEY GC, 1979, P SOC PHOTO-OPT INS, V197, P83
  • [3] A COMPACT RAMAN MICROPROBE MICROSCOPE - ANALYSIS OF POLYDIACETYLENE LANGMUIR AND LANGMUIR-BLODGETT-FILMS
    BATCHELDER, DN
    CHENG, C
    MULLER, W
    SMITH, BJE
    [J]. MAKROMOLEKULARE CHEMIE-MACROMOLECULAR SYMPOSIA, 1991, 46 : 171 - 179
  • [4] LINE-SCANNED MICRO RAMAN-SPECTROSCOPY USING A COOLED CCD IMAGING DETECTOR
    BOWDEN, M
    GARDINER, DJ
    RICE, G
    GERRARD, DL
    [J]. JOURNAL OF RAMAN SPECTROSCOPY, 1990, 21 (01) : 37 - 41
  • [5] NEAR-IR IMAGING OF ATHEROMAS IN LIVING ARTERIAL TISSUE
    CASSIS, LA
    LODDER, RA
    [J]. ANALYTICAL CHEMISTRY, 1993, 65 (09) : 1247 - 1256
  • [6] THE USE OF A NEAR-INFRARED ARRAY DETECTOR FOR RAMAN-SPECTROSCOPY BEYOND ONE MICRON
    CHASE, B
    TALMI, Y
    [J]. APPLIED SPECTROSCOPY, 1991, 45 (06) : 929 - 931
  • [7] COX IJ, 1982, OPTIK, V60, P391
  • [8] DUVALL J, 1987, P SOC PHOTO-OPT INS, V685, P121
  • [9] FORREST WJ, 1986, NASA88213 TECH MEM
  • [10] FUJISADA H, 1992, P SOC PHOTO-OPT INS, V1341, P80