DIELECTRIC-CONSTANT OF PHOSPHOLIPID-BILAYERS AND THE PERMEABILITY OF MEMBRANES TO IONS

被引：138

作者：

DILGER, JP ^{[1
]}

MCLAUGHLIN, SGA ^{[1
]}

MCINTOSH, TJ ^{[1
]}

SIMON, SA ^{[1
]}

机构：

[1] DUKE UNIV,DEPT ANAT ANESTHESIOL & PHYSIOL,DURHAM,NC 27710

来源：

SCIENCE | 1979年 / 206卷 / 4423期

关键词：

D O I：

10.1126/science.228394

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The Born charging equation predicts that the permeability of a phospholipid bilayer membrane to ions should depend markedly on the dielectric constant of the membrane. Increasing the dielectric constant of an artificial bilayer increases its permeability to perchlorate or thiocyanate by a factor of 1000, to a value comparable to that of mitochondrial membranes. Copyright © 1979 AAAS.

引用

页码：1196 / 1198

页数：3

共 15 条

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