EFFECT OF INFLUENZA VACCINATION ON PLASMA PHENYTOIN CONCENTRATIONS

被引：15

作者：

SAWCHUK, RJ

RECTOR, TS

FORDICE, JJ

LEPPIK, IE

机构：

[1] Department of Neurology, University of Minnesota, Minneapolis, MN

[2] Anoka State Hospital, Anoka, MN

来源：

THERAPEUTIC DRUG MONITORING | 1979年 / 1卷 / 02期

关键词：

Influenza vaccination; Phenytoin; Plasma concentration;

D O I：

10.1097/00007691-197901020-00010

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A mean decrease in plasma phenytoin concentrations of 11-14% (p < 0.005) was observed in seven patients within 4 days after influenza vaccination. Possible mechanisms are discussed. © Raven Press, New York.

引用

页码：285 / 288

页数：4

共 6 条

[1]

Barry D.W., Mayner R.E., Hochstein H.D., Dunlop R.C., Rastogi S.C., Hannah J.E., Blackburn R.J., Sullivan J.L., Gerety R.J., Comparative trial of influenza vaccines: Adverse reactions in children and adults, Am J Epidemiol, 104, pp. 47-59, (1976)

[2]

Hunter R.A., Status epilepticus: History, incidence and problems, Epilepsia, 1, pp. 162-188, (1959)

[3]

Leppik I.E., Ramani V., Sawchuk R.J., Gumnit R.J., Increased clearance of phenytoin during infectious mononucleosis, N Engl J Med, 300, pp. 481-482, (1979)

[4]

Renton K.W., The deleterious effect of Bordetella pertussis vaccine and poly(Rl.RC) on the metabolism and disposition of phenytoin, J Pharmacol Exp Ther, 208, pp. 267-270, (1979)

[5]

Hvidberg E.F., Dam M., Clinical pharmacokinetics of anticonvulsants, Clin Phar-Macokinet, 1, pp. 161-188, (1976)

[6]

Ludden T.M., Allen J.P., Scheider L.W., Stavchansky S.A., Rate of phenytoin accumulation in man: A simulation study, J Pharmucokinet Biopharm, 6, pp. 399-415, (1978)

← 1 →