CHARACTERIZATION OF PLASMIDS EXTRACTED FROM AIDS - ASSOCIATED MYCOBACTERIUM-AVIUM ISOLATES

被引：9

作者：

MORRIS, SL ^{[1
]}

ROUSE, DA ^{[1
]}

MALIK, A ^{[1
]}

CHAPARAS, SD ^{[1
]}

WITEBSKY, FG ^{[1
]}

机构：

[1] NIH,WARREN GRANT MAGNUSON CLIN CTR,BETHESDA,MD 20892

来源：

TUBERCLE | 1990年 / 71卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0041-3879(90)90073-H

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The plasmid profiles of 12 Mycobacterium avium strains isolated from 12 different patients with acquired immunodeficiency syndrome were analysed. Plasmids were identified in 9 of these strains. Plasmids were isolated from all 7 serovars 4 and 8 strains, a serovar 20a strain and an untypeable strain, but were not detected in either of 2 serovar 3b strains or an untypeable isolate. Southern blot hybridisations revealed that extracts derived from all of the plasmid-containing strains hybridised to a DNA probe prepared from known mycobacterial plasmid sequences. However, restriction analyses suggest that native plasmids which hybridised to the DNA probe and were similar in mass were not identical. © 1990.

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页码：181 / 185

页数：5

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