DISTRIBUTION AND ROLES OF PURINOCEPTOR SUBTYPES

被引：76

作者：

BURNSTOCK, G ^{[1
]}

机构：

[1] UNIV LONDON UNIV COLL, CTR NEUROSCI, LONDON WC1E 6BT, ENGLAND

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 1991年 / 10卷 / 05期

关键词：

D O I：

10.1080/07328319108047230

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The basis of the established subdivision of receptors for purines into P1-purinoceptors for adenosine and P2-purinoceptors for ATP and ADP is considered, as well as the proposals for subdivision of P1-purinoceptors into A1 and A2 subtypes and of ATP receptors into P2X-, P2Y-, P2Z- and P2T-purinoceptor subtypes. The distribution and roles of these receptor subtypes in muscles, nerves and other tissues, including endothelial and epithelial cells, hepatocytes, blood cells, fibroblasts and astrocytes, are discussed.

引用

页码：917 / 930

页数：14

共 85 条

[1] THE ACTIONS OF ADENOSINE 5'-TRIPHOSPHATE ON GUINEA-PIG INTRACARDIAC NEURONS IN CULTURE [J].

ALLEN, TGJ ;

BURNSTOCK, G .

BRITISH JOURNAL OF PHARMACOLOGY, 1990, 100 (02) :269-276

[2] ATP-ACTIVATED CHANNELS GATE CALCIUM ENTRY IN SINGLE SMOOTH-MUSCLE CELLS DISSOCIATED FROM RABBIT EAR ARTERY [J].

BENHAM, CD .

JOURNAL OF PHYSIOLOGY-LONDON, 1989, 419 :689-701

[3] A NOVEL RECEPTOR-OPERATED CA-2+-PERMEABLE CHANNEL ACTIVATED BY ATP IN SMOOTH-MUSCLE [J].

BENHAM, CD ;

TSIEN, RW .

NATURE, 1987, 328 (6127) :275-278

[4]

BERRIE CP, 1989, MOL PHARMACOL, V35, P526

[5] IDENTIFICATION OF P2Y PURINOCEPTORS ASSOCIATED WITH VOLTAGE-ACTIVATED CATION CHANNELS IN CARDIAC VENTRICULAR MYOCYTES OF THE RAT [J].

BJORNSSON, OG ;

MONCK, JR ;

WILLIAMSON, JR .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1989, 186 (1-2) :395-404

[6]

BO X, 1990, IN PRESS BR J PHARM

[7] [H-3] ALPHA, BETA-METHYLENE ATP, A RADIOLIGAND LABELING P2-PURINOCEPTORS [J].

BO, XO ;

BURNSTOCK, G .

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1989, 28 (01) :85-88

[8] P2 PURINOCEPTORS ON VASCULAR ENDOTHELIAL-CELLS - PHYSIOLOGICAL SIGNIFICANCE AND TRANSDUCTION MECHANISMS [J].

BOEYNAEMS, JM ;

PEARSON, JD .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1990, 11 (01) :34-37

[9] LYMPHOCYTE MEMBRANE ADENOSINE RECEPTORS COUPLED TO ADENYLATE-CYCLASE PROPERTIES AND OCCURRENCE IN VARIOUS LYMPHOCYTE SUBCLASSES [J].

BONNAFOUS, JC ;

DORNAND, J ;

FAVERO, J ;

MANI, JC .

JOURNAL OF RECEPTOR RESEARCH, 1981, 2 (04) :347-366

[10]

BURNSTOCK G, 1988, P1

← 1 2 3 4 5 6 7 8 9 →