SERUM TETRAIODOTHYROACETATE (T4A) LEVELS IN NORMAL HEALTHY EUTHYROID INDIVIDUALS DETERMINED BY GAS CHROMATOGRAPHY-MASS FRAGMENTOGRAPHY (GC-MF)

被引：12

作者：

CROSSLEY, DN

RAMSDEN, DB

机构：

[1] Department of Medicine, University of Birmingham, Queen Elizabeth Hospital, Birmingham

来源：

CLINICA CHIMICA ACTA | 1979年 / 94卷 / 03期

关键词：

D O I：

10.1016/0009-8981(79)90074-3

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A gas chromatography-mass fragmentography (GC-MF) assay for T4A in human serum is described. The assay involves a multistage extraction, followed by conversion of T4A to its dimethyl derivative prior to GC-MF. Using this assay, the concentration of T4A in 37 normal euthyroid subjects was, mean ± S.D., 114.5 ± 26.4 pmol/l, which is considerably lower than previous reports. Thyroxine binding prealbumin (TBPA) did not appear to be a major determinant of T4A concentration. © 1979.

引用

页码：267 / 272

页数：6

共 16 条

[1]

BARKER SB, 1956, P SOC EXP BIOL MED, V91, P650

[2]

BURGER A, 1976, LANCET, V1, P653

[3]

BURGER A, 1973, 5 P ANN M EUR THYR A, P38

[4] CONCENTRATION OF THYROXINE-BINDING GLOBULIN - VALUE OF DIRECT ASSAY [J].