PROTECTION AGAINST ALZHEIMERS-DISEASE WITH APOE EPSILON-2

被引：208

作者：

TALBOT, C ^{[1
]}

LENDON, C ^{[1
]}

CRADDOCK, N ^{[1
]}

SHEARS, S ^{[1
]}

MORRIS, JC ^{[1
]}

GOATE, A ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,DEPT NEUROL,ST LOUIS,MO 63117

来源：

LANCET | 1994年 / 343卷 / 8910期

关键词：

D O I：

10.1016/S0140-6736(94)92557-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1432 / 1433

页数：2

共 5 条

[1] APOLIPOPROTEIN-E, EPSILON-4 ALLELE AS A MAJOR RISK FACTOR FOR SPORADIC EARLY AND LATE-ONSET FORMS OF ALZHEIMERS-DISEASE - ANALYSIS OF THE 19Q13.2 CHROMOSOMAL REGION [J].

CHARTIERHARLIN, MC ;

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GOURLET, V ;

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DELACOURTE, A ;

ROSSOR, M ;

AMOUYEL, P .

HUMAN MOLECULAR GENETICS, 1994, 3 (04) :569-574

[2] GENE DOSE OF APOLIPOPROTEIN-E TYPE-4 ALLELE AND THE RISK OF ALZHEIMERS-DISEASE IN LATE-ONSET FAMILIES [J].

CORDER, EH ;

SAUNDERS, AM ;

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SCIENCE, 1993, 261 (5123) :921-923

[3] GENETIC ASSOCIATIONS WITH HUMAN LONGEVITY AT THE APOE AND ACE LOCI [J].

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COHEN, D .

NATURE GENETICS, 1994, 6 (01) :29-32

[4] INCREASED AMYLOID BETA-PEPTIDE DEPOSITION IN CEREBRAL-CORTEX AS A CONSEQUENCE OF APOLIPOPROTEIN-E GENOTYPE IN LATE-ONSET ALZHEIMER-DISEASE [J].

SCHMECHEL, DE ;

SAUNDERS, AM ;

STRITTMATTER, WJ ;

CRAIN, BJ ;

HULETTE, CM ;

JOO, SH ;

PERICAKVANCE, MA ;

GOLDGABER, D ;

ROSES, AD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (20) :9649-9653

[5] BINDING OF HUMAN APOLIPOPROTEIN-E TO SYNTHETIC AMYLOID-BETA PEPTIDE - ISOFORM-SPECIFIC EFFECTS AND IMPLICATIONS FOR LATE-ONSET ALZHEIMER-DISEASE [J].

STRITTMATTER, WJ ;

WEISGRABER, KH ;

HUANG, DY ;

DONG, LM ;

SALVESEN, GS ;

PERICAKVANCE, M ;

SCHMECHEL, D ;

SAUNDERS, AM ;

GOLDGABER, D ;

ROSES, AD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (17) :8098-8102

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