DETERMINATION OF KINETIC PARAMETERS OF RED BLOOD CELL SURVIVAL BY COMPUTER SIMULATION

被引：7

作者：

GARBY, L

GROTH, T

SCHNEIDER, W

机构：

[1] The Swedish Medical Research Council Unit for Experimental Haematology, University Hospital, Uppsala

[2] Institute of Physics, University of Uppsala

[3] Computer Center, University of Uppsala

来源：

COMPUTERS AND BIOMEDICAL RESEARCH | 1969年 / 2卷 / 03期

关键词：

D O I：

10.1016/0010-4809(69)90004-4

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

From a stochastic point of view, red blood cell survival can be completely characterized by two functions: one describing the death probability and the other the production rate of cells. These functions yield expressions for measurable quantities, e.g., the total amount of circulating cells, and can therefore be determined by comparison with experimental data. The successful application of direct and indirect computer simulation to this problem is reported together with suitable methods for parameter estimation. In addition to the death probability and the production rate, these methods also yield the corresponding frequency functions for the life span and the age of the cells. The methods are applicable in stationary as well as nontationary conditions. © 1969.

引用

页码：229 / +

页数：1

共 9 条

[1] STOCHASTIC INTERPRETATION OF CELL SURVIVAL CURVES [J].