EVALUATION OF THE RISK OF PELVIC INFECTION FOLLOWING TRANSVAGINAL OOCYTE RECOVERY

被引:14
作者
CURTIS, P
AMSO, N
KEITH, E
BERNARD, A
SHAW, RW
机构
[1] Academic Department of Obstetrics and Gynaecology, Royal Free Hospital, Hampstead, London NW3 2QG, Pond Street
关键词
TRANSVAGINAL OOCYTE RECOVERY; INFECTION; ZIFT; UNEXPLAINED INFERTILITY;
D O I
10.1093/oxfordjournals.humrep.a137530
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The risk of introducing infection into the peritoneal cavity at the time of transvaginal ultrasound-guided recovery of oocytes in assisted reproduction techniques was assessed by culturing peritoneal fluid samples from 25 women with unexplained infertility. The samples were collected laparoscopically at the time of zygote intra-Fallopian transfer (ZIFT, 24-48 h after oocyte collection. High vaginal and endocervical specimens from 25 women treated by in-vitro fertilization (IVF) and transcervical embryo transfer were cultured for comparison. The peritoneal cultures were negative in all but one patient. High vaginal swabs grew Candida albicans in three cases and endocervical specimens were all negative. Seven and three pregnancies occurred in the ZIFT and IVF groups respectively. No pelvic damage was noted at laparoscopy in those women who had had previous treatment cycles with transvaginal oocyte recovery. This method of oocyte recovery, using prophylactic metronidazole and chlorhexidine for preoperative vaginal preparation, appears to be safe for treatment of women with no previous pelvic damage.
引用
收藏
页码:1294 / 1297
页数:4
相关论文
共 16 条
[1]  
Daschner F.D., Petersen E.E., Frank U., Homig D., Penetration of cefmenoxime into serum, gynecologic tissues, and heart valves, Am, J, Med, TJ, pp. 4-6, (1984)
[2]  
De Grandi P., Bauen J.F., Pharmacokinetics of ceftriaxone in serum and gynaecological tissues, Chemotherapy, 32, pp. 473-477, (1986)
[3]  
Devroey P., Braeckmans P., Smitz J., Van Waesberghe L., Wisanto A., Van Steirteghem A.C., Pregnancy after trans-laparoscopic zygote intrafallopian transfer in a patient with sperm antibodies, Lancet, 1, (1986)
[4]  
Feichtinger W., Kemeter P., Transvaginal sector scan sonography for needle guided transvaginal follicle aspiration and other applications in gynecologic routine and research, Fertil, Steril, 45, (1986)
[5]  
Henry-Suchet J., Utzmann C., De Brux J., Ardoin P., Catalan F., Microbiologic study of chronic inflammation associated with tubal factor infertility: Role of Chlamydia trachomatis, Fertil, Steril, 47, pp. 274-277, (1987)
[6]  
Howe R.S., Wheeler C., Mastroianni L., Blasco L., Tureck R., Pelvic infection after transvagina] ultrasound-guided ovum retrieval, Fertil, Steril, 49, pp. 726-728, (1988)
[7]  
Kapur R.P., Johnson L., An oviductal fluid glycoprotein associated with ovulated mouse ova and early embryos, Dev, Biol, 112, pp. 89-93, (1985)
[8]  
Lenz S., Leeton J., Renou P., Transvaginal recovery of oocytes for in vitro fertilisation using vaginal ultrasound, J, Vitro Fertii Embryo Transfer, 4, pp. 51-55, (1987)
[9]  
Meldrum D.R., Antibiotics for vaginal oocyte aspiration, J, Vitro Fertil, Embryo Transfer, 6, pp. 1-2, (1989)
[10]  
Ripa K.T., Merdh P.-A., New simplified culture technique for Chlamydia trachomatis, Nongonococcal Urethritis and Related Infections, American Society for Microbiology, pp. 323-327, (1977)