EMERGENCE OF VIP RHYTHMICITY FOLLOWING SOMATOSTATIN DEPLETION IN THE RAT SUPRACHIASMATIC NUCLEUS

被引：25

作者：

FUKUHARA, C

NISHIWAKI, T

CAGAMPANG, RFA

INOUYE, SIT

机构：

[1] SOPHIA UNIV,INST LIFE SCI,TOKYO 102,JAPAN

[2] KYOTO UNIV,CTR ECOL RES,OTSU,SHIGA 52001,JAPAN

来源：

BRAIN RESEARCH | 1994年 / 645卷 / 1-2期

关键词：

VASOACTIVE INTESTINAL POLYPEPTIDE; SOMATOSTATIN; CIRCADIAN RHYTHM; SUPRACHIASMATIC NUCLEUS; CYSTEAMINE; ENZYME IMMUNOASSAY; RAT;

D O I：

10.1016/0006-8993(94)91671-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Administration of a somatostatin (SS) depletor, cysteamine, markedly reduced SS levels in rat suprachiasmatic nucleus (SCN). At the same time, cysteamine administration induced a circadian rhythm of vasoactive intestinal polypeptide (VIP) content in the SCN, which otherwise remains constant under constant environmental conditions. These results suggest that the stable level of VIP in the SCN under constant conditions is not an intrinsic property of VIP neurons but a consequence of interactions with other components in the SCN.

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页码：343 / 346

页数：4

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