MULTIPLE SITES AND SYNERGISM IN THE BINDING OF INHIBITORS TO MICROSOMAL AMINOPEPTIDASE

被引：14

作者：

DIGREGORIO, M ^{[1
]}

PICKERING, DS ^{[1
]}

CHAN, WWC ^{[1
]}

机构：

[1] MCMASTER UNIV,DEPT BIOCHEM,HAMILTON L8N 3Z5,ONTARIO,CANADA

来源：

BIOCHEMISTRY | 1988年 / 27卷 / 10期

关键词：

D O I：

10.1021/bi00410a013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3613 / 3617

页数：5

共 27 条

[1] KINETIC-PARAMETERS OF METAL-SUBSTITUTED LEUCINE AMINOPEPTIDASE FROM BOVINE LENS [J].

ALLEN, MP ;

YAMADA, AH ;

CARPENTER, FH .

BIOCHEMISTRY, 1983, 22 (16) :3778-3783

[2] HYDROXAMATES AND ALIPHATIC BORONIC ACIDS - MARKER INHIBITORS FOR AMINOPEPTIDASE [J].

BAKER, JO ;

WILKES, SH ;

BAYLISS, ME ;

PRESCOTT, JM .

BIOCHEMISTRY, 1983, 22 (09) :2098-2103

[3] PREPARATION OF CHLOROMETHYLKETONE ANALOGS OF AMINO-ACIDS - INHIBITION OF LEUCINE AMINOPEPTIDASE [J].

BIRCH, PL ;

AKHTAR, M ;

ELOBEID, HA .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1972, 148 (02) :447-&

[4] FUNCTION OF METAL ION IN LEUCINE AMINOPEPTIDASE + MECHANISM OF ACTION OF ENZYME [J].

BRYCE, GF ;

RABIN, BR .

BIOCHEMICAL JOURNAL, 1964, 90 (03) :513-&

[5]

CHAN WWC, 1982, J BIOL CHEM, V257, P7955

[6] L-LEUCINTHIOL - A POTENT INHIBITOR OF LEUCINE AMINOPEPTIDASE [J].

CHAN, WWC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 116 (01) :297-302

[7] AMINO-ACID HYDROXAMATES AS INHIBITORS OF THE HUMAN ENKEPHALIN-DEGRADING AMINOPEPTIDASE [J].

COLETTIPREVIERO, MA ;

DEPAULET, AC ;

MATTRAS, H ;

PREVIERO, A .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 107 (02) :465-469

[8] DESIGN OF POTENT COMPETITIVE INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME - CARBOXYALKANOYL AND MERCAPTOALKANOYL AMINO-ACIDS [J].

CUSHMAN, DW ;

CHEUNG, HS ;

SABO, EF ;

ONDETTI, MA .

BIOCHEMISTRY, 1977, 16 (25) :5484-5491

[9]

Delange R. J., 1971, ENZYMES, VIII, P81

[10] IDENTIFICATION OF AMINOPEPTIDASE-M AS AN ENKEPHALIN-INACTIVATING ENZYME IN RAT CEREBRAL MEMBRANES [J].

GROS, C ;

GIROS, B ;

SCHWARTZ, JC .

BIOCHEMISTRY, 1985, 24 (09) :2179-2185

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