CHROMOSOMAL ASSIGNMENT OF THE HUMAN GENES-CODING FOR THE MAJOR PROTEINS OF THE DESMOSOME JUNCTION, DESMOGLEIN DGI (DSG), DESMOCOLLINS DGII/III (DSC), DESMOPLAKINS DPI/II (DSP), AND PLAKOGLOBIN DPIII (JUP)

被引：71

作者：

ARNEMANN, J

SPURR, NK

WHEELER, GN

PARKER, AE

BUXTON, RS

机构：

[1] NATL INST MED RES,EUKARYOT MOLEC GENET LAB,MILL HILL,LONDON NW7 1AA,ENGLAND

[2] IMPERIAL CANC RES FUND,CLARE HALL LABS,POTTERS BAR EN6 3LD,HERTS,ENGLAND

来源：

GENOMICS | 1991年 / 10卷 / 03期

关键词：

D O I：

10.1016/0888-7543(91)90446-L

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

We have established PCR assays for the genes coding for the major proteins of the desmosome type of cell junction, the desmosomal cadherins DGI (desmoglein) and DGII III (desmocollins), and the plaque proteins DPI II (desmoplakin) and DPIII (plakoglobin) and used them to test human-mouse and human-rat somatic cell hybrids with different contents of human chromosomes. From these data we were able to assign DGI to chromosome 18 (DSG), DGII III to chromosome 9p (DSC), DPI II to chromosome 6p21-ter(DSP), and DPIII to chromosome 7 (JUP). © 1991.

引用

页码：640 / 645

页数：6

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